The introduction of anti-vascular endothelial growth factor (VEGF) agents has revolutionized therapy for a host of ocular diseases associated with leakage from normal blood vessels and pathologic blood vessel growth. Anti-VEGF Use in Ophthalmology is an all-inclusive reference designed to provide detailed, up-to-date, and clinically relevant information on the current use of anti-VEGF agents in the treatment of all ocular conditions.
Drs. Jay S. Duker and Michelle C. Liang have assembled a prestigious group of contributors who pool their collective expertise in this comprehensive book. Anti-VEGF Use in Ophthalmology is split into two sections with the first providing the history of VEGF and an overview of anti-VEGF agents and different routes of drug delivery, as it is important for eye care providers to be familiar with up-to-date aspects of the medications and indications for use.
The second section details the clinical uses of anti-VEGF agents in numerous ocular diseases, from the anterior segment including cornea and glaucoma to uveitis and various retinal and choroidal diseases. Each chapter in this section summarizes the disease process and utilizes high-quality ocular imaging to demonstrate the therapeutic use of the anti-VEGF agents.
Some of the topics covered in Anti-VEGF Use in Ophthalmology:
- Neovascular Age-Related Macular Degeneration
- Proliferative Diabetic Retinopathy
- Retinal Vein Occlusion
- Neovascular Glaucoma
- Macular Edema
- Retinopathy of Prematurity
- Corneal Disease
Anti-VEGF Use in Ophthalmology combines the theory and applications of anti-VEGF agents, making it not only a great learning tool for beginners but also a useful reference tool for a wide range of eye care professionals including optometrists, residents, comprehensive ophthalmologists, as well as specialists in anterior segment, pediatrics, and vitreoretinal disease.
This book is a concise guide to the prevention and management of post-surgical ocular infections covering both common and serious conditions. Divided into 24 chapters, the text begins with discussion on preventive aspects including an introduction to the operating theatre, air flow and water requirements, and patient and personnel preparation. The following sections describe the diagnosis, treatment and prevention of infections resulting from different ocular surgeries. This practical guide is highly illustrated with clinical photographs and flow charts highlighting significant aspects of prevention and management. Key points * Concise guide to prevention and management of post-surgical ocular infections * Covers both common and serious conditions resulting from different types of surgery * Explains basic preventive measures relating to the operating theatre and personnel * Highly illustrated with clinical photographs and flow charts
This reader-friendly and well-illustrated book is a concise clinical reference on the management of severe ocular injuries. It will serve as an ideal guide for clinicians dealing with trauma and ophthalmology, assisting in the implementation of individualized treatment strategies and the performance of up-to-date surgical interventions. Easy-to-follow instructions are provided on the management of each injured tissue of the globe, with emphasis on key pearls and pitfalls that must be borne in mind in order to achieve an optimal anatomical and functional outcome. Both common and rare causes of injury are covered, including mass casualty incidents, and current concepts regarding the evaluation and classification of injury mechanisms are fully taken into consideration. In addition, each chapter pays special attention to hot topics and medicolegal issues in patient management.
Endophthalmitis is a serious eye infection that can cause blindness if not promptly diagnosed and appropriately treated. The goals of this book are to provide the latest information about endophthalmitis and offer recommendations for diagnosis and treatment.
Each chapter is written by experts in the field with the practicing clinician in mind. Several chapters focus on the major types of endophthalmitis such as postoperative, post-intravitreal injection, bleb-related, exogenous fungal, chronic, and endogenous endophthalmitis. Other chapters describe endophthalmitis in special populations such as diabetic or immunocompromised hosts or those with a glaucoma drainage device, keratoprosthesis, or other artificial implant. Also included are chapters that provide an overview of endophthalmitis as seen around the world, summarize current understanding of endophthalmitis pathogenesis, describe the latest microbiologic and molecular diagnostic techniques, and discuss emerging problems such as multidrug-resistant pathogens. A final chapter offers recommendations for ways to prevent this devastating eye infection.
This book provides a concise overview over the pathology of retinal angiogenic diseases and explains why anti-angiogenic therapy is effective in so many patients. The reader is guided through the various clinical indications for anti-angiogenic therapy and made aware of its merits as well as current challenges and limitations. It is explained how, since its introduction for the treatment of exudative age-related macular degeneration in 2006, anti-angiogenic therapy has revolutionized the way in which we treat a range of ocular diseases. All of the authors are established experts in their respective fields who share their extensive knowledge and clinical experience with the reader. This book is both a valuable introduction to anti-angiogenic therapy in ophthalmology and a day-to-day companion for all ophthalmologists seeing patients with some of the most prevalent retinal diseases.
This book describes experimental animal models that mimic common human ocular diseases: herpetic keratitis, cataract, glaucoma, age-related macular degeneration, diabetic retinopathy, uveitis, retinitis pigmentosa, Graves’ disease, and intraocular tumors. In conjunction, these models reflect the diversity and utility of tools used to study human disease. World expert clinicians discuss each model based on their clinical experience and the text is supported by numerous photos and diagrams. In describing the most pertinent animal models of ophthalmic diseases, this book will be of interest to ophthalmologists, vision researchers, fellows, residents and medical students.
Stem Cells in Ophthalmologydescribes a wide range of therapeutic applications of stem cells in ophthalmological treatments. This book is written and edited by distinguished international authors, who have drawn heavily on their in-depth academic knowledge, practical experience and research.
Comprised of 17 chapters, the book initially covers basic stem cell biology and immunity, proceeding to detail the use of stem cell therapy to regenerate all the structures of the visual system and ocular adnexa. Immunologic factors, such as antigen identification and functional rejection pathways are discussed in detail. The book also details practice of translational medicine and facilities, and governmental requirements needed to establish an ocular stem cell program.
Stem Cells in Ophthalmologygives extensive coverage to the regenerative use of stem cells in ophthalmology. Enhanced by 84 colour images and illustrations, this is an essential resource for ophthalmologists and stem cell therapists.
84 full colour images and illustrations
Covers all structures of the visual system in detail
Edited by pan-American team of ophthalmology experts from Argentina, USA and Brazil
This is a practical manual for diagnostic testing, focusing on the historical and contemporary research on functional disorders in general, and functional visual disorders in particular. Functional Ophthalmic Disorders: Ocular Malingering and Visual Hysteria is a how-to manual that is written for the practicing ophthalmologist and optometrist, complete with color photos that allow the reader to see pictures of select diseases. In addition to the photos, videos are provided online to illustrate the various tests and possible results conducted on a mock patient to assist in the differential diagnosis. Written and edited by leaders in the field, some of the topics covered include history of functional disorders, ophthalmologic examination in malingering and techniques and tests for functional and simulated defects.
This book focuses on the different aspects of ophthalmology – the medical science of diagnosis and treatment of eye disorders. Ophthalmology is divided into various clinical subspecialties, such as cornea, cataract, glaucoma, uveitis, retina, neuro-ophthalmology, pediatric ophthalmology, oncology, pathology, and oculoplastics.
This book offers ophthalmologists and medical practitioners a concise, data-driven review of the information that is most relevant in guiding the diagnosis and management of thyroid eye disease (TED). Particular attention is devoted to research and clinical trials that have advanced the field in recent years.
Progress in our understanding of the pathogenesis of TED is described, and the heterogeneous natural history of TED is discussed to facilitate preemptive interventions. Advances in diagnostic evaluation, including autoantibody assessment, are reviewed with regard to their clinical utility. The diagnostic features of euthyroid TED are also carefully covered since these patients often represent a diagnostic dilemma.
All relevant aspects of treatment are addressed including the role of radioactive iodine, long-term medical therapy, and surgical thyroidectomy. The impact of these treatment modalities on eye disease are discussed. Management of active TED is reviewed according to the severity of disease and in the light of recent findings and the introduction of novel agents. The discussion encompasses the role of steroids and other agents, the use of novel biologics, the medical and surgical treatment of optic neuropathy, and minimally invasive, customized reconstructive surgery. Numerous supporting images are included, and helpful checklists will aid the practitioner in treatment decision making.
The Handbook of Nutrition, Diet and the Eye is the first book to thoroughly address common features and etiological factors in how dietary and nutritional factors affect the eye.
The ocular system is perhaps one of the least studied organs in diet and nutrition, yet the consequences of vision loss can be devastating. One of the biggest contributors to complete vision loss in the western hemisphere is diabetes, precipitated by metabolic syndrome. In some developing countries, micronutrient deficiencies are major contributory factors to impaired vision. However, there are a range of ocular defects that have either their origin in nutritional deficiencies or excess or have been shown to respond favorably to nutritional components. The eye from the cornea to the retina may be affected by nutritional components. Effects may be physiological or molecular.
This book represents essential reading for nutritionists, dietitians, optometrists, ophthalmologists, opticians, endocrinologists, and other clinicians and researchers interested in eye health and vision in general.
Saves clinicians and researchers time in quickly accessing the very latest details on a broad range of nutrition, ocular health, and disease issuesProvides a common language for nutritionists, nutrition researchers, optometrists, and ophthalmologists to discuss how dietary and nutritional factors, and related diseases and syndromes affect the eyePreclinical, clinical, and population studies will help nutritionists, dieticians, and clinicians map out key areas for research and further clinical recommendations
The vitreous body long has been the most mysterious of all ocular structures, owing perhaps to its seeming simplicity. There have been few concerted, sustained efforts to unravel the mysteries of how vitreous is composed and what role it plays in normal physiology as well as pathology. Over the years, however, many studies have produced important findings concerning vitreous biochemistry, structure, physiology, and pathobiology. Published on the 25th anniversary of Sebag’s first book on Vitreous, this second installment is nearly five times longer than its predecessor, reflecting how much has been learned in the past quarter century. This well-constructed compendium not only addresses the most current scientific knowledge, but also reviews clinical perspectives in a manner that lends richness to the scope of the book.
Written by 90 authors, this book has 56 chapters organized into 7 sections: Biochemistry; Anatomy, Development, and Aging; Pathology/Pathobiology; Physiology and Phamacotherapy; Posterior Vitreo-Retinal Surgery; Peripheral Vitreo-Retinal Surgery; and Pharmacologic Vitreolysis. With a foreword by Coleman & Lincoff and an introduction by Wallace Foulds, Sebag’s latest tome on vitreous is destined to be the authoritative text for years to come.
This handbook is a concise, easy-to-read, practical guide that conveys the core knowledge necessary to diagnose, classify, grade, and manage dry eye disease effectively and efficiently. A series of succinct, informative chapters cover the following key topics: definition and classification, epidemiology, office-based screening and diagnostics, artificial tears, medical management, surgical management, and future directions. Current guidelines, published studies, and the personal experience of internationally recognized dry eye experts are distilled into practical tips that will be of value during daily clinical routine. Highlighted boxes are included to emphasize the most important points or clinical pearls, and tables and flow charts will further assist the eye care practitioner in using the book as a quick reference. The closing chapter presents case examples that build upon the instruction provided earlier in the book by illustrating the optimal approach to diverse scenarios that may be encountered in the clinic.
This book explains how to use intravitreal steroids optimally in the management of patients with intraocular inflammation (uveitis) and macular edema. The rationale for this treatment approach is first explained by examining the pathophysiology of these disease entities, with particular attention to the major role of inflammatory processes. Devices for the delivery of steroids to the eye are discussed, and guidance provided on the role of imaging studies before, during, and after steroid therapy. The value of different steroidal approaches is then considered in detail. Other topics addressed include the use of steroids as a surgical adjunct and within a combination strategy. Uveitis and macular edema are common sight-threatening diseases or complications of diabetes and retinal vein occlusion for which no adequate treatment was available until recently. Both trainees and practitioners will find Intravitreal Steroids to be an invaluable aid in combating these blinding diseases.
The innate immune system comprises the cells and mechanisms that are the first line of defence against infection by other organisms. This book provides a comprehensive synopsis of eye diseases, their immunological mechanisms and the role of the immune cells and mediators. Beginning with an introduction to the role of the innate immune system, the following chapters discuss the different types of immune cells in the eye and their role in the etiopathogenesis of various diseases including glaucoma and age-related macular degeneration. Edited by Manfred Zierhut, recognised expert from the University of Tuebingen Germany, this book is presented in an easy to read format, enabling practitioners to understand even the most sophisticated eye disorders from an immunological perspective. Key points * Comprehensive synopsis of the role of the innate immune system in eye diseases * Covers different types of immune cells * Edited by internationally recognised specialist in Germany
This is a timely, accurate, clinically relevant and extraordinarily well illustrated volume. It is a superb source of current clinical knowledge for the busy practicing ophthalmologists who are in the trenches caring for patients on a daily basis. Both medical and surgical topics are covered such as: cornea, external diseases, cataract surgery including the recently available femtosecond laser, lens implant surgery, glaucoma, retina and vitreous. The depth and breadth of the information presented is intended to bring the reader current with the newest diagnostic and therapeutic approaches in our rapidly advancing field.
Lacrimal disorders are one of the very common conditions encountered not only by the oculoplastic surgeons but also by the general ophthalmologists in their daily practice. Written by global experts in the field of dacyrology, this book is a comprehensive, updated practical guide on evaluation and management of patients with lacrimal diseases. This up-to-date reference work covers all aspects of the field including the basic anatomy and underlying pathology, evaluation of a patient, and all surgical procedures currently used in managing various disorders in an organized fashion. Surgical modalities including the endoscopic approaches are thoroughly and succinctly reviewed with ample illustrations for better understanding. Since familiarity with a surgical technique is incomplete without the knowledge of risk factors and red flags, an emphasis on dealing with surgical complications and failure has received priority in this treatise. Controversial topics and treatment dilemmas have been discussed in detail with the objective of reviewing the present consensus among the experts.